Best Juices for Anti-Aging

Bergamot juice, mulberry juice, and persimmon juice are three candidates for anti-aging, but none is proven to slow aging in people. If you have a health concern, the ai symptom analyzer can help you organize questions, but it cannot diagnose a condition or replace medical care.

These juices have been included in preliminary research on aging-related processes. For a broader look at options beyond juice, see the best drinks for anti-aging.

Which 3 juices are candidates for anti-aging?

The three juices below are starting points, not a proven ranking. The available studies tested extracts, cells or animals, rather than measuring whether people who drink these juices age more slowly. There is also no reliable comparison showing that one is better than another.

A juice may contain useful plant compounds, but its composition depends on the fruit and how it is processed. A result from a particular extract or fermented product should not be assumed to apply to every juice on a store shelf.

Bergamot juice

Potential mechanism: Bergamot contains plant compounds that researchers have investigated for their effects on oxidative stress. Oxidative stress is involved in many biological processes associated with aging, but changing a marker of it in a laboratory is not the same as slowing aging in a person.

How to use it: Look for food-grade bergamot juice intended for drinking. It can be quite tart, so you may prefer it diluted with water; check the label for added sugar if you buy a blend. Do not substitute bergamot essential oil for juice.

Bergamot juice may be harder to find than more familiar fruit juices. There is no demonstrated anti-aging reason to seek it out if you dislike it or cannot find a suitable product. Eating a variety of fruit is a practical alternative.

Strength of evidence: laboratory only. In a 2023 laboratory study, researchers exposed human red blood cells to conditions intended to model aspects of aging and tested bergamot peel and juice extracts. The work examined oxidative-stress markers in cells; it did not test people drinking bergamot juice.

Those findings cannot establish that a serving of juice protects skin, prevents age-related disease or extends life. The extract and the conditions used in the laboratory also differ from what happens when a person digests a drink.

Mulberry juice

Potential mechanism: Mulberries contain polyphenols, plant compounds that can be altered during fermentation. Researchers are interested in how these compounds and their byproducts interact with biological processes, including oxidative stress, but that interest does not establish an anti-aging effect in people.

How to use it: Choose pasteurized mulberry juice without added sugar when available, and check whether the product is mostly mulberry or a blend. Serve a small portion with a meal or dilute it with water if you prefer a less sweet drink. Whole mulberries can also contribute fruit and fiber to the diet.

The type of product matters when interpreting the research. Ordinary mulberry juice, a fermented mulberry drink and the laboratory product used in a study are not interchangeable. A label mentioning fermentation or polyphenols is not proof that a drink has the effects reported by researchers.

Strength of evidence: animal study. A 2024 study of fermented mulberry juice used a mouse model of aging. Researchers reported changes in oxidative-stress measures and performance on a maze test, among other findings.

The study did not show that mulberry juice improves memory or slows aging in humans. It also tested a specifically fermented product, so its results cannot be applied automatically to unfermented juice. Human studies would be needed before recommending mulberry juice for an anti-aging outcome.

Persimmon juice

Potential mechanism: Persimmons contain plant compounds, including polyphenols, that can be investigated in antioxidant and cell experiments. These tests can help researchers identify compounds worth studying, but they do not show how much reaches human tissues after someone drinks juice or whether it produces a meaningful benefit.

How to use it: If buying persimmon juice, look for a pasteurized product and check the ingredients. Some products may combine persimmon with other fruits or sweeteners, which makes them different from juice made only from persimmons. Choose based on taste and the overall nutrition of your diet, not an anti-aging claim.

Whole, ripe persimmons are another way to enjoy the fruit. Straining fruit to make juice can remove some of its fiber, so juice should not routinely displace whole fruit in the hope of a greater anti-aging effect. The study below does not establish that juice is superior to the fruit.

Strength of evidence: laboratory only. A 2014 laboratory study of fruit and herb preparations included two persimmon varieties in antioxidant and cell-based tests. The research used prepared extracts and did not measure aging outcomes in people who drank persimmon juice.

The varieties and preparations tested may also differ from a commercial product. It is therefore too early to say that persimmon juice prevents wrinkles, protects the skin from aging or has any particular anti-aging effect.

How much juice should you drink?

There is no established anti-aging dose for any of these juices. As a practical portion, you could start with 4 fluid ounces, or about 120 mL, and decide whether it fits your usual meals and preferences. This is a serving suggestion, not a proven effective dose or a universal daily limit.

Choose juice made from fruit rather than assuming a product advertised for anti-aging has special benefits. Check for added sugar and serving size, and remember that even 100% fruit juice contains naturally occurring sugars. Diluting juice with water changes the drink's sweetness and volume, but it does not remove the sugar from the juice used.

Whole fruit is generally a better way to get the fruit's fiber. If you enjoy juice, consider it one part of an overall eating pattern rather than a replacement for a variety of fruit and other foods. More juice is not known to produce more anti-aging benefit.

Acidic juices, including citrus juices, can contribute to tooth enamel erosion. Having them with a meal instead of sipping them throughout the day, and rinsing your mouth with water afterward, can reduce how often your teeth are exposed to acid.

No juice can replace established habits that support health as you age, such as regular physical activity, adequate sleep, a balanced diet and protection from excessive sun exposure. There is no need to drink juice at all to follow those habits.

Who should be careful with juice?

If you have diabetes or another condition that affects blood glucose, remember that juice can raise blood sugar. Ask your clinician or a registered dietitian how a portion fits your eating plan, and follow your usual monitoring advice. Do not change or stop medication because you have added juice to your diet.

If you have kidney disease or have been told to limit potassium or fluids, ask your care team whether a particular juice and portion are suitable. If you take medication with food or juice restrictions, check with a pharmacist or clinician before trying a new juice, including bergamot juice.

Pregnant people, children and people with weakened immune systems should avoid unpasteurized juice because it can carry harmful germs. Ask a child's pediatrician about whether juice is appropriate, particularly for a young child.

See a clinician about persistent or unexplained symptoms rather than trying to manage them with an anti-aging drink. An unexplained change in weight, ongoing fatigue or a changing skin lesion deserves medical attention; juice is not a diagnostic test or treatment.